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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R2
All Species:
13.64
Human Site:
S205
Identified Species:
33.33
UniProt:
Q13319
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13319
NP_003927.1
367
38705
S205
C
Y
R
L
K
E
L
S
P
G
E
L
V
G
W
Chimpanzee
Pan troglodytes
XP_516099
367
38658
S205
C
Y
R
L
K
E
L
S
P
G
E
L
V
G
W
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
E157
E
L
L
R
C
L
G
E
F
L
C
R
R
C
Y
Dog
Lupus familis
XP_853120
458
47635
S293
C
Y
R
L
K
E
L
S
P
G
E
L
V
G
W
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
S205
C
Y
R
L
K
E
L
S
P
G
E
L
V
G
W
Rat
Rattus norvegicus
P61810
307
34013
E157
E
L
L
R
C
L
G
E
F
L
C
R
R
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089375
320
35634
F170
L
L
R
C
L
G
E
F
V
C
R
R
C
Y
R
Zebra Danio
Brachydanio rerio
NP_001017569
308
34577
D157
E
L
L
R
C
L
S
D
F
M
C
R
R
C
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
V200
P
I
A
E
Q
E
N
V
P
S
E
A
S
T
S
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
L222
Q
T
N
P
K
K
I
L
Q
C
S
T
S
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
49.5
77.2
N.A.
94.3
48.7
N.A.
N.A.
N.A.
58.3
55.5
N.A.
N.A.
N.A.
31.6
36.5
Protein Similarity:
100
99.7
59.1
77.7
N.A.
94.8
58.5
N.A.
N.A.
N.A.
64.5
64.8
N.A.
N.A.
N.A.
42.5
49.8
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
40
0
0
10
30
0
0
0
0
20
30
0
10
30
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
30
0
0
10
0
50
10
20
0
0
50
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
30
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
20
0
0
40
0
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
50
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
40
30
40
10
30
40
10
0
20
0
40
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
50
30
0
0
0
0
0
0
10
40
30
0
10
% R
% Ser:
0
0
0
0
0
0
10
40
0
10
10
0
20
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
0
0
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% W
% Tyr:
0
40
0
0
0
0
0
0
0
0
0
0
0
10
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _